Bicheng Chen Selected Research

Dopamine (Intropin)

10/2014	Elevated dopamine induces minimal hepatic encephalopathy by activation of astrocytic NADPH oxidase and astrocytic protein tyrosine nitration.
1/2014	The inactivation of JAK2/STAT3 signaling and desensitization of M1 mAChR in minimal hepatic encephalopathy (MHE) and the protection of naringin against MHE.
7/2013	Dopamine from cirrhotic liver contributes to the impaired learning and memory ability of hippocampus in minimal hepatic encephalopathy.

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Bicheng Chen Research Topics

Disease

26	Pancreatic Neoplasms (Pancreatic Cancer) 02/2022 - 01/2014
23	Neoplasms (Cancer) 02/2022 - 01/2014
17	Liver Cirrhosis (Hepatic Cirrhosis) 12/2020 - 02/2012
15	Pancreatitis 03/2020 - 02/2008
11	Inflammation (Inflammations) 07/2022 - 12/2013
11	Fibrosis (Cirrhosis) 04/2022 - 02/2012
8	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 01/2016
6	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2014
5	Carcinogenesis 01/2022 - 01/2016
5	Ureteral Obstruction 07/2017 - 06/2014
4	Acute Lung Injury 03/2020 - 12/2013
4	Lung Injury 03/2020 - 12/2013
4	Diabetes Mellitus 01/2020 - 01/2016
3	Hypoxia (Hypoxemia) 01/2020 - 01/2016
3	Disease Progression 01/2018 - 07/2015
3	Hepatic Encephalopathy 10/2014 - 07/2013
2	Insulin Resistance 11/2021 - 01/2019
2	Kidney Diseases (Kidney Disease) 01/2021 - 12/2014
2	Atrophy 04/2020 - 01/2020
2	Pleural Effusion (Pleural Effusions) 03/2020 - 08/2014
2	Stomach Neoplasms (Stomach Cancer) 01/2020 - 01/2019
2	Autoimmune Diseases (Autoimmune Disease) 10/2019 - 01/2016
2	Hyperglycemia 10/2019 - 01/2018
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2018 - 08/2014
2	Chronic Hepatitis B 01/2017 - 08/2015
2	Arteriosclerosis 01/2016 - 06/2012
2	Pathologic Constriction (Stenosis) 01/2016 - 01/2012
2	Fatigue 04/2015 - 01/2013
2	Acute Necrotizing Pancreatitis 05/2013 - 02/2008
2	Portal Hypertension 01/2012 - 04/2010
1	Body Weight (Weight, Body) 01/2022
1	Gestational Diabetes (Gestational Diabetes Mellitus) 11/2021
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2021
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2021

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 12/2021 - 05/2011
12	MicroRNAs (MicroRNA)IBA 12/2020 - 01/2014
11	Biomarkers (Surrogate Marker)IBA 11/2021 - 10/2012
6	Interleukin-6 (Interleukin 6)IBA 01/2021 - 10/2012
6	lipoxin A4IBA 01/2019 - 02/2011
6	Matrix Metalloproteinases (MMPs)IBA 01/2017 - 01/2014
5	Pharmaceutical PreparationsIBA 02/2022 - 01/2016
5	CreatinineIBA 01/2022 - 06/2014
5	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2018
5	CytokinesIBA 01/2016 - 12/2013
4	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2018 - 01/2015
3	aristolochic acid I (aristolochic acid)IBA 01/2021 - 06/2014
3	Taurocholic Acid (Sodium Taurocholate)IBA 03/2020 - 02/2008
3	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2020 - 01/2019
3	Biological ProductsIBA 01/2020 - 01/2015
3	Insulin (Novolin)FDA Link 10/2019 - 01/2016
3	LuteolinIBA 09/2018 - 01/2015
3	ErbB Receptors (EGF Receptor)IBA 07/2018 - 08/2014
3	trichostatin A (A 300)IBA 04/2018 - 11/2014
3	Long Noncoding RNAIBA 11/2017 - 01/2017
3	VimentinIBA 01/2017 - 01/2015
3	CateninsIBA 01/2017 - 01/2016
3	Cadherins (E-Cadherin)IBA 01/2017 - 01/2015
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 01/2014
3	Dopamine (Intropin)FDA LinkGeneric 10/2014 - 07/2013
2	ResveratrolIBA 04/2022 - 12/2014
2	Urea (Carbamide)FDA LinkGeneric 01/2022 - 04/2020
2	NitrogenIBA 01/2022 - 04/2020
2	Blood Glucose (Blood Sugar)IBA 01/2022 - 01/2022
2	AntioxidantsIBA 01/2021 - 03/2020
2	Messenger RNA (mRNA)IBA 01/2021 - 05/2018
2	Caspase 3 (Caspase-3)IBA 08/2020 - 01/2015
2	Sirolimus (Rapamycin)FDA Link 04/2020 - 05/2011
2	Sildenafil Citrate (Viagra)FDA Link 03/2020 - 07/2014
2	Tacrolimus (Prograf)FDA LinkGeneric 01/2020 - 10/2019
2	DNA (Deoxyribonucleic Acid)IBA 10/2019 - 08/2015
2	InterferonsIBA 10/2019 - 01/2019
2	Antineoplastic Agents (Antineoplastics)IBA 01/2019 - 01/2015
2	LipoxinsIBA 11/2018 - 02/2011
2	cobaltous chloride (cobalt(II)chloride)IBA 09/2018 - 01/2016
2	Gefitinib (Iressa)FDA Link 07/2018 - 08/2017
2	Gemcitabine FDA Link 05/2018 - 01/2018
2	theasinensin AIBA 04/2018 - 01/2015
2	Histone Deacetylase InhibitorsIBA 04/2018 - 01/2015
2	brusatolIBA 01/2018 - 10/2017
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 11/2017 - 01/2015
2	p38 Mitogen-Activated Protein KinasesIBA 10/2017 - 12/2013
2	CollagenIBA 07/2017 - 01/2016
2	Amylases FDA Link 01/2017 - 01/2016
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 05/2016 - 01/2014
2	SolanineIBA 01/2016 - 01/2014
2	salvianolic acid BIBA 01/2016 - 11/2015
1	Factor XI (Plasma Thromboplastin Antecedent)IBA 07/2022
1	agrimoniinIBA 02/2022
1	AlbuminsIBA 01/2022
1	Triglycerides (Triacylglycerol)IBA 11/2021
1	Dimethyl FumarateIBA 01/2021
1	Thrombopoietin (c-mpl Ligand)IBA 01/2021
1	nirogacestatIBA 01/2021
1	Streptozocin (Streptozotocin)FDA Link 01/2021

Therapy/Procedure

12	Therapeutics 01/2022 - 06/2012
8	Islets of Langerhans Transplantation 01/2022 - 01/2016
6	Drug Therapy (Chemotherapy) 02/2022 - 08/2014
5	Transplantation 01/2022 - 01/2015
2	Intra-Arterial Infusions 01/2014 - 05/2013
1	Radiotherapy 02/2022